Spatial modeling and simulation in cell biology

Spatial Statistical Modeling in Biology

Simulation in spatial analysis and modeling

GeoComputation is an evolving research field with a primary focus on exploring new modeling paradigms and techniques derived from advances in computation for the goal of enriching geographic analysis of highly complex, and often non-deterministic problems (Longley, 1998). Agent-based models, cellular automata, fuzzy sets, genetic algorithms, and neural networks have attracted attention as usefu...

Cell Biology Modeling Development

The fundamental problem of pattern formation for example, how to specify body axes, limbs, digits during development comes down to interpreting a common set of genetic instructions differently at different locations in space (Wolpert 1969). (See Figure 1.1 for an illustration). In all multicellular animals, this process is orchestrated by morphogens, molecules that are produced at discrete site...

Modeling Neural Stem Cell and Glioma Biology

Bergström, T. 2013. Modeling Neural Stem Cell and Glioma Biology. Acta Universitatis Upsaliensis. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 924. 63 pp. Uppsala. ISBN 978-91-554-8719-5. This thesis is focused on neural stem cell (NSC) and glioma biology. I discuss how NSCs interact with extracellular matrix (ECM) proteins in the stem cell niche, and in...

a study on rate making and required reserves determination in reinsurance market: a simulation

reinsurance is widely recognized as an important instrument in the capital management of an insurance company as well as its risk management tool. this thesis is intended to determine premium rates for different types of reinsurance policies. also, given the fact that the reinsurance coverage of every company depends upon its reserves, so different types of reserves and the method of their calc...